Chemicals & pollution

Hazardous Substance

Meaning statusEstablishedSource recordDirect document linkedWhy these are different

Definition

A hazardous substance is a chemical substance or mixture that meets classification criteria for physical hazards (such as flammability or explosivity), health hazards (such as toxicity, carcinogenicity, or corrosivity), or environmental hazards (such as aquatic toxicity). The UN Globally Harmonized System of Classification and Labelling of Chemicals (GHS) provides the worldwide reference rules for classifying such hazards and communicating them through labels and safety data sheets.

References

CCOHSGlobally Harmonized System (GHS) — UN-developed rules for classifying hazards of chemical products and communicating them via labels and safety data sheets

classification and communication system

Overview

What it means

Before GHS, the same chemical could be labelled carcinogenic in one country and not another; harmonised classification made hazard communication comparable across borders and supply chains. In the EU, GHS is implemented through the CLP Regulation, while REACH governs registration and risk management of substances placed on the market.

How it is used

Classification determines labelling, transport rules, workplace exposure controls, and downstream-user obligations; the term anchors chemicals management in both environmental and occupational law.

Why it matters

Common hazard language is the precondition for managing the world's chemical inventory safely.

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Meaning status
Established
Verification date
Not recorded
Last updated
18 Aug 2026
What the classifications mean

Meaning status: Established

EstablishedCurrentMultiple definitionsContestedEmergingIndexed