Chapter 02 · Nature, land & waterWater, Waste & Pollution

Chemical of Concern

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Definition

A chemical identified as warranting priority attention — restriction, substitution or phase-out — because of hazardous properties such as carcinogenicity, mutagenicity, reproductive toxicity (CMR), persistence and bioaccumulation (PBT/vPvB) or equivalent concern such as endocrine disruption. The EU REACH Regulation's Substances of Very High Concern (SVHCs, Article 57) are the regulatory archetype; industry usage (CoC/CoHC) extends to substances on customer, NGO or sector lists beyond law.

References

ECHACandidate List of substances of very high concern

Supports definition and framing.

Overview

What it means

"Chemical of concern" is the working category between regulatory bans and free use — substances flagged by hazard science ahead of, or beyond, legal restriction. REACH operationalises the concept: SVHC identification leads to the Candidate List (over 240 substances, updated roughly twice yearly), then potentially to the Authorisation List with sunset dates after which use requires permission.

Companies screen portfolios against multiple concern lists (Candidate List, SIN List, GreenScreen Benchmark-1, customer RSLs) because being caught with a soon-to-be-restricted substance is a financial risk; the category thus functions as an early-warning system driving safer-by-design substitution.

How it is used

Procurement and R&D teams run list-based screening of formulations; disclosure duties attach (REACH's 0. 1% w/w communication threshold, SCIP database); investors use CoC exposure as a regulatory-risk proxy; substitution programmes target CoCs first.

Why it matters

The CoC category converts hazard science into commercial signal — the mechanism by which markets anticipate regulation and pull safer chemistry forward.

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Meaning status
Established
Verification date
Not recorded
Last updated
18 Aug 2026
What the classifications mean

Meaning status: Established

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